Amgen has included data from 19 facilities covering energy and carbon, water and waste. The facilities represent approximately 94 percent of Amgen's worldwide facility space based on total square feet. Included facilities are in Thousand Oaks, California, U.S.; West Greenwich, Rhode Island, U.S.; Longmont, Colorado, U.S.; Bothell, Washington, U.S.; Juncos, Puerto Rico, U.S.; Louisville, Kentucky, U.S.; South San Francisco, California, U.S.; Cambridge and Woburn, Massachusetts, U.S.; Burnaby, Canada; Breda, Netherlands; Dun Laoghaire, Ireland; Uxbridge, Abingdon and Cambridge, United Kingdom; São Paulo, Brazil; Yenibosna and Sekerpinar, Turkey; and Tuas, Singapore. This includes leased buildings where we have operational control over building infrastructure, including utilities.
Measurement and verification of conservation and reduction projects for energy and carbon, water and waste are based on adaptation of the International Performance Measurement and Verification Protocol (IPMVP), Concepts and Options for Determining Energy and Water Savings Volume 1, EVO 10000-1.2007, April 2007. Project measurements are conducted using reasonable means, including direct measurements and scientific estimations as appropriate. Values for conservation and reduction projects represent year-over-year, cumulative and continuing avoidance based on a 2007 baseline, then rebaselined in 2012 to match the next-generation 2020 Target design. Results from conservation and reduction projects from sites in Brazil, Turkey and Singapore are not included in the 2016 data.
Immaterial changes to 2007–2016 data may have occurred due to refinements in calculations. All changes have been confirmed through a documented change control process.