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John Chung

Principal Scientist
Process Development

John Chung is a Principal Scientist within Amgen’s Drug Product Technologies organization.  He currently leads a group that develops and manufactures oral solid dosage forms for early stage clinical studies.  John is a subject matter expert on biopharmaceutics, the science of how orally dosed molecules are absorbed from the gastrointestinal tract into the body.  Prior to joining Amgen, John worked at Simulations Plus where he worked on the development of a physiologically based oral absorption modeling/simulation software used by pharmaceutical companies and regulatory agencies around the world. 

Featured Publications

Lou H, Chung JI, Kiang YH, Xiao LY, Hageman MJ. The Application of Machine Learning Algorithms in Understanding the Effect of Core/Shell Technique on Improving Powder Compactability Int J Pharm. 2019;555: 368-379. https://www.sciencedirect.com/science/article/pii/S0378517318308597?via%3Dihub

Chung J, Kesisoglou F. Physiologically Based Oral Absorption Modelling to Study Gut‐Level Drug Interactions J Pharm Sci. 2018 Jan;107(1):18‐2 https://www.sciencedirect.com/science/article/pii/S0022354917306111?via%3Dihub

Chung JI, Kelly RC, Wahlstrom J, Wu B, Wu T, Alvarez‐Nunez F. Maximizing the Impact of Physiologically Based Oral Absorption Modeling and Simulation. J Pharm Sci. 2017 Mar;106(3):734‐737 https://www.sciencedirect.com/science/article/pii/S0022354916418800

Kesisoglou F, Chung J, van Asperen J, Heimbach T. Physiologically Based Absorption Modeling to Impact Biopharmaceutics and Formulation Strategies in Drug Development‐Industry Case Studies J Pharm Sci. 2016 Sep;105(9):2723‐2734 https://www.sciencedirect.com/science/article/pii/S0022354915001495?via%3Dihub

Chung J, Alvarez‐Nunez F, Chow V, Daurio D, Davis J, Dodds M, Emery M, Litwiler K, Paccaly A, Peng J, Rock B, Wienkers L, Yang C, Yu Z, Wahlstrom J Utilizing physiologically based pharmacokinetic modeling to inform formulation and clinical development for a compound with pH‐dependent solubility J Pharm Sci. 2015 Apr;104(4):1522‐32 https://www.sciencedirect.com/science/article/abs/pii/S0022354915301751?via%3Dihub

Education

Ph.D., Doctor of Pharmacy, PharmD, Pharmaceutical Sciences, University of Michigan
B.S., Bioengineering, University of California- Berkeley