Obesity is a global health problem that increases risk for many related serious illnesses.1 These obesity-related conditions include Type 2 diabetes, heart and respiratory disease, as well as kidney and liver disease.2 Hundreds of millions of people worldwide are affected by obesity and obesity-related illness.3,4 These numbers could rise into the billions in coming decades.5

A complex and heterogenous disease, obesity affects different people in different ways. Effective strategies to treat obesity will likely require a variety of approaches. Addressing the needs of these patients is a challenge that we take seriously and view as critical for public health.

Our obesity initiatives include potential therapeutics that are in varying stages of research and development. These treatment approaches are diverse and tailored to meet the dynamic needs of patients with obesity, underscoring our commitment to innovation and patient care.

Discover More About Our Approach to Obesity

Obesity-Related Publications


  1. Health Effects of Overweight and Obesity in 195 Countries over 25 Years. The New England Journal of Medicine. 2017;377(1):13-27. doi:10.1056/nejmoa1614362
  2. Health Risks of Overweight & Obesity. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/weight-management/adult-overweight-obesity/health-risks. Published October 30, 2023. 
  3. World Health Organization: WHO. Obesity and overweight. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight. Published June 9, 2021. 
  4. Marck CH, Neate S, Taylor KL, Weiland TJ, Jelinek GA. Prevalence of Comorbidities, Overweight and Obesity in an International Sample of People with Multiple Sclerosis and Associations with Modifiable Lifestyle Factors. PLOS ONE. 2016;11(2):e0148573. doi:10.1371/journal.pone.0148573 
  5. Boutari C, Mantzoros CS. A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on. Metabolism. 2022;133:155217.